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Queen's University Belfast is a public research university in Belfast, Northern Ireland. The university's official title, per its charter, is The Queen's University of Belfast. It is often referred to simply as Queen's, or by the abbreviation QUB. The university was chartered in 1845, and opened in 1849 as "Queen's College, Belfast", but has roots going back to 1810 and the Royal Belfast Academical Institution.

Queen's is a member of the Russell Group of leading research intensive universities, the Association of Commonwealth Universities, the European University Association, Universities Ireland and Universities UK. The university offers academic degrees at various levels and across a broad subject range, with over 300 degree programmes available. Professor Patrick Johnston is the University’s 12th President and Vice-Chancellor since 1 March 2014, and its Chancellor is the current Secretary General of the Commonwealth of Nations, Kamalesh Sharma.

The University also forms the focal point of the Queen's Quarter area of the city, one of Belfast's seven cultural districts.

Queen's University Belfast has its roots in the Belfast Academical Institution, which was founded in 1810, one of the United Kingdom's 10 oldest universities, and remains as the Royal Belfast Academical Institution. The present university was first chartered as "Queen's College, Belfast" in 1845, when it was associated with the simultaneously founded Queen's College, Cork, and Queen's College, Galway, as part of the Queen's University of Ireland – founded to encourage higher education for Catholics and Presbyterians, as a counterpart to Trinity College, Dublin, then an Anglican institution. Queen's College, Belfast, opened in 1849. Its main building, the Lanyon Building, was designed by the English architect, Sir Charles Lanyon. At its opening, it had 23 professors and 343 students. Some early students at Queen's University Belfast took University of London examinations.

The Irish Universities Act, 1908 dissolved the Royal University of Ireland, which had replaced the Queen's University of Ireland in 1879, and created two separate universities: the current National University of Ireland and Queen's University of Belfast.

Queen's has been led by a distinguished line of Vice-chancellors, including Sir David Keir, Lord Ashby of Brandon, Dr Michael Grant, Sir Arthur Vick, Sir Peter Froggatt, Sir Gordon Beveridge, Sir George Bain and Professor Sir Peter Gregson.

The university's Chancellors have included Anthony Ashley-Cooper, 9th Earl of Shaftesbury, Field Marshal Alan Brooke, 1st Viscount Alanbrooke, Sir Tyrone Guthrie, Eric Ashby, Baron Ashby, and George J. Mitchell. The incumbent is Kamalesh Sharma.